Autoimmune blood tests, also known as autoantibody tests, play a vital role in diagnosing various immune system disorders in South Africa. These tests involve analysing blood samples to detect specific antibodies that target the body’s own tissues and organs. They help clinicians identify conditions such as rheumatoid arthritis, lupus, and multiple sclerosis. In South African medical facilities, healthcare professionals rely on these tests to assess the presence and severity of autoimmune diseases, allowing for timely intervention and personalised treatment plans. The accuracy and reliability of autoimmune blood tests have significantly improved the management of these complex conditions in our diverse population, ensuring better health outcomes for patients across the Rainbow Nation.